| | | |
| October 12, 2024 | L | Charlotte Checkers 7 at Wilkes-Barre/Scranton Penguins 6 | Final |
| October 13, 2024 | W | Wilkes-Barre/Scranton Penguins 4 at Springfield Thunderbirds 1 | Final |
| October 18, 2024 | W | Lehigh Valley Phantoms 3 at Wilkes-Barre/Scranton Penguins 4 | Final |
| October 19, 2024 | W | Wilkes-Barre/Scranton Penguins 3 at Lehigh Valley Phantoms 0 | Final |
| October 25, 2024 | L | Wilkes-Barre/Scranton Penguins 0 at Syracuse Crunch 2 | Final |
| October 26, 2024 | W | Syracuse Crunch 2 at Wilkes-Barre/Scranton Penguins 3 | Final |
| October 30, 2024 | W | Wilkes-Barre/Scranton Penguins 4 at Bridgeport Islanders 3 | Final (SO) |
| November 2, 2024 | W | Hartford Wolf Pack 1 at Wilkes-Barre/Scranton Penguins 2 | Final |
| November 6, 2024 | W | Lehigh Valley Phantoms 1 at Wilkes-Barre/Scranton Penguins 2 | Final (OT) |
| November 8, 2024 | L | Wilkes-Barre/Scranton Penguins 3 at Lehigh Valley Phantoms 5 | Final |
| November 9, 2024 | W | Rochester Americans 0 at Wilkes-Barre/Scranton Penguins 5 | Final |
| November 13, 2024 | L | Wilkes-Barre/Scranton Penguins 3 at Lehigh Valley Phantoms 4 | Final (OT) |
| November 16, 2024 | L | Bridgeport Islanders 5 at Wilkes-Barre/Scranton Penguins 2 | Final |
| November 22, 2024 | W | Bridgeport Islanders 0 at Wilkes-Barre/Scranton Penguins 5 | Final |
| November 29, 2024 | W | Laval Rocket 3 at Wilkes-Barre/Scranton Penguins 5 | Final |
| November 30, 2024 | W | Wilkes-Barre/Scranton Penguins 5 at Hershey Bears 4 | Final |
| December 4, 2024 | L | Hershey Bears 6 at Wilkes-Barre/Scranton Penguins 1 | Final |
| December 7, 2024 | W | Wilkes-Barre/Scranton Penguins 6 at Hartford Wolf Pack 2 | Final |
| December 8, 2024 | L | Wilkes-Barre/Scranton Penguins 0 at Providence Bruins 5 | Final |
| December 11, 2024 | W | Charlotte Checkers 4 at Wilkes-Barre/Scranton Penguins 6 | Final |
| December 13, 2024 | L | Charlotte Checkers 4 at Wilkes-Barre/Scranton Penguins 0 | Final |
| December 14, 2024 | W | Springfield Thunderbirds 4 at Wilkes-Barre/Scranton Penguins 5 | Final (OT) |
| December 18, 2024 | L | Toronto Marlies 3 at Wilkes-Barre/Scranton Penguins 0 | Final |
| December 21, 2024 | W | Lehigh Valley Phantoms 2 at Wilkes-Barre/Scranton Penguins 7 | Final |
| December 22, 2024 | W | Wilkes-Barre/Scranton Penguins 1 at Hershey Bears 0 | Final |
| December 27, 2024 | W | Lehigh Valley Phantoms 2 at Wilkes-Barre/Scranton Penguins 3 | Final |
| December 28, 2024 | L | Wilkes-Barre/Scranton Penguins 2 at Hershey Bears 3 | Final (OT) |
| January 3, 2025 | L | Charlotte Checkers 3 at Wilkes-Barre/Scranton Penguins 2 | Final (OT) |
| January 4, 2025 | W | Hartford Wolf Pack 0 at Wilkes-Barre/Scranton Penguins 5 | Final |
| January 8, 2025 | W | Wilkes-Barre/Scranton Penguins 6 at Toronto Marlies 3 | Final |
| January 10, 2025 | W | Wilkes-Barre/Scranton Penguins 6 at Belleville Senators 1 | Final |
| January 12, 2025 | L | Wilkes-Barre/Scranton Penguins 3 at Belleville Senators 4 | Final |
| January 15, 2025 | L | Wilkes-Barre/Scranton Penguins 3 at Laval Rocket 4 | Final (OT) |
| January 24, 2025 | L | Wilkes-Barre/Scranton Penguins 3 at Utica Comets 5 | Final |
| January 25, 2025 | W | Utica Comets 1 at Wilkes-Barre/Scranton Penguins 2 | Final |
| January 26, 2025 | W | Lehigh Valley Phantoms 1 at Wilkes-Barre/Scranton Penguins 5 | Final |
| January 29, 2025 | W | Hershey Bears 0 at Wilkes-Barre/Scranton Penguins 9 | Final |
| January 31, 2025 | L | Wilkes-Barre/Scranton Penguins 2 at Charlotte Checkers 3 | Final |
| February 1, 2025 | W | Wilkes-Barre/Scranton Penguins 3 at Charlotte Checkers 2 | Final |
| February 7, 2025 | W | Bridgeport Islanders 0 at Wilkes-Barre/Scranton Penguins 3 | Final |
| February 8, 2025 | W | Cleveland Monsters 4 at Wilkes-Barre/Scranton Penguins 5 | Final (OT) |
| February 11, 2025 | L | Wilkes-Barre/Scranton Penguins 4 at Hershey Bears 5 | Final |
| February 14, 2025 | L | Lehigh Valley Phantoms 3 at Wilkes-Barre/Scranton Penguins 2 | Final (SO) |
| February 15, 2025 | L | Hershey Bears 4 at Wilkes-Barre/Scranton Penguins 3 | Final (OT) |
| February 16, 2025 | W | Wilkes-Barre/Scranton Penguins 4 at Lehigh Valley Phantoms 3 | Final |
| February 21, 2025 | W | Wilkes-Barre/Scranton Penguins 4 at Hartford Wolf Pack 1 | Final |
| February 22, 2025 | L | Wilkes-Barre/Scranton Penguins 3 at Springfield Thunderbirds 5 | Final |
| February 23, 2025 | L | Wilkes-Barre/Scranton Penguins 4 at Providence Bruins 5 | Final (OT) |
| February 26, 2025 | L | Wilkes-Barre/Scranton Penguins 2 at Rochester Americans 5 | Final |
| February 28, 2025 | W | Wilkes-Barre/Scranton Penguins 2 at Syracuse Crunch 0 | Final |
| March 1, 2025 | L | Wilkes-Barre/Scranton Penguins 4 at Hershey Bears 5 | Final (OT) |
| March 4, 2025 | L | Belleville Senators 4 at Wilkes-Barre/Scranton Penguins 1 | Final |
| March 7, 2025 | W | Wilkes-Barre/Scranton Penguins 7 at Hartford Wolf Pack 1 | Final |
| March 8, 2025 | W | Belleville Senators 3 at Wilkes-Barre/Scranton Penguins 8 | Final |
| March 9, 2025 | L | Syracuse Crunch 5 at Wilkes-Barre/Scranton Penguins 1 | Final |
| March 12, 2025 | W | Hershey Bears 4 at Wilkes-Barre/Scranton Penguins 5 | Final (SO) |
| March 14, 2025 | L | Wilkes-Barre/Scranton Penguins 1 at Lehigh Valley Phantoms 3 | Final |
| March 16, 2025 | W | Wilkes-Barre/Scranton Penguins 5 at Lehigh Valley Phantoms 3 | Final |
| March 21, 2025 | L | Providence Bruins 10 at Wilkes-Barre/Scranton Penguins 2 | Final |
| March 22, 2025 | W | Hershey Bears 2 at Wilkes-Barre/Scranton Penguins 3 | Final (OT) |
| March 23, 2025 | W | Wilkes-Barre/Scranton Penguins 5 at Bridgeport Islanders 2 | Final |
| March 26, 2025 | W | Hartford Wolf Pack 3 at Wilkes-Barre/Scranton Penguins 4 | Final (OT) |
| March 29, 2025 | W | Wilkes-Barre/Scranton Penguins 5 at Charlotte Checkers 3 | Final |
| March 30, 2025 | L | Wilkes-Barre/Scranton Penguins 2 at Charlotte Checkers 5 | Final |
| April 4, 2025 | L | Wilkes-Barre/Scranton Penguins 1 at Cleveland Monsters 7 | Final |
| April 5, 2025 | L | Wilkes-Barre/Scranton Penguins 0 at Cleveland Monsters 3 | Final |
| April 11, 2025 | L | Hershey Bears 4 at Wilkes-Barre/Scranton Penguins 2 | Final |
| April 12, 2025 | W | Springfield Thunderbirds 1 at Wilkes-Barre/Scranton Penguins 4 | Final |
| April 13, 2025 | W | Wilkes-Barre/Scranton Penguins 5 at Bridgeport Islanders 2 | Final |
| April 16, 2025 | L | Providence Bruins 3 at Wilkes-Barre/Scranton Penguins 2 | Final |
| April 18, 2025 | L | Wilkes-Barre/Scranton Penguins 2 at Hershey Bears 4 | Final |
| April 19, 2025 | W | Cleveland Monsters 0 at Wilkes-Barre/Scranton Penguins 3 | Final |
| April 23, 2025 | L | Lehigh Valley Phantoms 5 at Wilkes-Barre/Scranton Penguins 2 (Playoff Gm. 1) | Final |
| April 25, 2025 | L | Wilkes-Barre/Scranton Penguins 2 at Lehigh Valley Phantoms 3 (Playoff Gm. 2) | Final |
Wilkes-Barre/Scranton Penguins Schedule
