| | | |
| March 14, 2025 | W | Chicago Stars FC 0 at Orlando Pride 6 | Final |
| March 23, 2025 | W | Orlando Pride 2 at NJ/NY Gotham FC 0 | Final |
| March 29, 2025 | W | San Diego Wave FC 1 at Orlando Pride 2 | Final |
| April 12, 2025 | W | Orlando Pride 1 at Seattle Reign FC 0 | Final |
| April 19, 2025 | L | Washington Spirit 1 at Orlando Pride 0 | Final |
| April 25, 2025 | W | Angel City FC 2 at Orlando Pride 3 | Final |
| May 3, 2025 | | Orlando Pride at Portland Thorns FC | 7:30 p.m. |
| May 10, 2025 | | Orlando Pride at North Carolina Courage | 7:30 p.m. |
| May 16, 2025 | | Kansas City Current at Orlando Pride | 8:00 p.m. |
| May 23, 2025 | | Orlando Pride at Utah Royals FC | 9:30 p.m. |
| June 7, 2025 | | Houston Dash at Orlando Pride | 7:00 p.m. |
| June 13, 2025 | | Orlando Pride at Bay FC | 10:00 p.m. |
| June 20, 2025 | | Orlando Pride at Racing Louisville FC | 8:00 p.m. |
| August 3, 2025 | | Utah Royals FC at Orlando Pride | 6:00 p.m. |
| August 9, 2025 | | Racing Louisville FC at Orlando Pride | 7:30 p.m. |
| August 16, 2025 | | Orlando Pride at Kansas City Current | 4:00 p.m. |
| August 21, 2025 | | Orlando Pride at Angel City FC | 10:30 p.m. |
| August 29, 2025 | | NJ/NY Gotham FC at Orlando Pride | 8:00 p.m. |
| September 7, 2025 | | Orlando Pride at Chicago Stars FC | 3:00 p.m. |
| September 13, 2025 | | Bay FC at Orlando Pride | 5:00 p.m. |
| September 19, 2025 | | North Carolina Courage at Orlando Pride | 7:30 p.m. |
| September 26, 2025 | | Orlando Pride at San Diego Wave FC | 10:30 p.m. |
| October 3, 2025 | | Orlando Pride at Houston Dash | 8:00 p.m. |
| October 10, 2025 | | Portland Thorns FC at Orlando Pride | 8:00 p.m. |
| October 18, 2025 | | Orlando Pride at Washington Spirit | 12:30 p.m. |
| November 2, 2025 | | Seattle Reign FC at Orlando Pride | TBD |
Orlando Pride Schedule
